Yes, with StudioEdge you can output your StudioEdge video conferencing callers to NDI only, or simultaneously as outputting via SDI. This is set up within the SETTINGS window of each individual channel.
If you do not need SDI outputs of your callers, select the Video Input and select NDI.
If you wish to simultaneously output your video conferencing callers to NDI and SDI, make sure the correct SDI device is selected in Video Input, then toggle the NDI Output option.